The substance P encoding gene preprotachykinin A modulates fenestrations in the liver sinusoidal endothelial cells in polymicrobial sepsis in mice


Background: Sepsis is a life-threatening condition caused by infection. Substance P (SP), encoded by the preprotachykinin A (PPTA) gene, acts as an inflammatory mediator in sepsis. Fenestrated liver sinusoidal endothelial... [ view full abstract ]


  1. Ravinder Reddy Gaddam (University of Otago-Christchurch)
  2. Stephen Chambers (University of Otago-Christchurch)
  3. Robin Fraser (University of Otago-Christchurch)
  4. Victoria Cogger (ANZAC Research Institute, University of Sydney)
  5. David Le Couteur (ANZAC Research Institute, University of Sydney)
  6. Madhav Bhatia (University of Otago-Christchurch)

Topic Area

Liver sinusoidal liver cells in liver disease


PS » Poster Session & Lunch (12:45 - Friday, 16th June, Aula Maxima, 1st Floor)