Alcohol-induced macrophage apoptosis modulates the intrahepatic inflammatory phenotype and limits liver inflammation

Abstract

The transcription factor FOXO3 serves as an alcohol protection factor but the mechanisms are unknown. We previously demonstrated that ethanol causes selective phosphorylation of FOXO3 that enhances its ability to induce... [ view full abstract ]

Authors

  1. Zhuan Li (University of Kansas Medical Center)
  2. Jie Zhao (University of Kansas Medical Center)
  3. Shujun Zhang (University of Kansas Medical Center)
  4. Steven Weinman (University of Kansas Medical Center)

Topic Area

Liver sinusoidal liver cells in liver disease

Session

OS6 » Session 6 Alcohol & Other Liver Injuries (09:00 - Friday, 16th June, Aula Maxima, Ground Floor)