Human pluripotent stem cell-derived mesenchymal stem cells contribute to liver regeneration in Gunn rats

Abstract

Mesenchymal stem cells (MSCs) are used in many clinical trials to improve liver function in chronic diseases, due to their immune suppressive and trophic properties. In addition, MSCs are multipotent cells and able to... [ view full abstract ]

Authors

  1. Claus Kordes (University of Duesseldorf, Heinrich Heine, Clinic for Gastroenterology, Hepatology and Infectious Diseases)
  2. Lucas Sebastian Spitzhorn (University of Duesseldorf, Heinrich Heine, Institute for Stem Cell Research and Regenerative Medicine)
  3. Matthias Megges (University of Duesseldorf, Heinrich Heine, Institute for Stem Cell Research and Regenerative Medicine)
  4. Silke Götze (University of Duesseldorf, Heinrich Heine, Clinic for Gastroenterology, Hepatology and Infectious Diseases)
  5. Iris Sawitza (University of Duesseldorf, Heinrich Heine Universtiy, Clinic for Gastroenterology, Hepatology and Infectious Diseases)
  6. Doreen Reichert (University of Duesseldorf, Heinrich Heine Universtiy, Clinic for Gastroenterology, Hepatology and Infectious Diseases)
  7. Peggy Schultze-Matz (University of Duesseldorf, Heinrich Heine, Institute for Stem Cell Research and Regenerative Medicine)
  8. Nina Graffmann (University of Duesseldorf, Heinrich Heine, Institute for Stem Cell Research and Regenerative Medicine)
  9. Martina Bohndorf (University of Duesseldorf, Heinrich Heine, Institute for Stem Cell Research and Regenerative Medicine)
  10. Wasco Wruck (University of Duesseldorf, Heinrich Heine, Institute for Stem Cell Research and Regenerative Medicine)
  11. Jan Philipp Köhler (University of Duesseldorf, Heinrich Heine, Clinic for Gastroenterology, Hepatology and Infectious Diseases)
  12. Diran Herebian (University of Duesseldorf, Heinrich Heine, Department of General Pediatrics, Neonatolgy and Pediatric Cardiology)
  13. Ertan Mayatepek (University of Duesseldorf, Heinrich Heine, Department of General Pediatrics, Neonatolgy and Pediatric Cardiology)
  14. Richard O. C. Oreffo (University of Southampton, Centre for Human Development, Stem Cells and Regeneration)
  15. James Adjaye (University of Duesseldorf, Heinrich Heine, Institute for Stem Cell Research and Regenerative Medicine)
  16. Dieter Häussinger (University of Duesseldorf, Heinrich Heine, Clinic for Gastroenterology, Hepatology and Infectious Diseases)

Topic Area

Liver regeneration

Session

OS8 » Session 8 Liver Regeneration (09:30 - Saturday, 17th June, Aula Maxima, Ground Floor)