Apoptosis signal-regulating kinase (ASK1) is a novel therapeutic target for NASH


Background: ASK1 is a redox-sensitive kinase that is activated by pathological stimuli including oxidative and ER stress. ASK1 promotes activation of p38 and JNK MAP kinases to induce hepatocyte apoptosis, hepatic inflammation... [ view full abstract ]


  1. Grant Budas (Gilead Sciences Inc.)

Topic Area

Liver fibrosis


OS7 » Session 7 Liver Fibrosis - 2 (11:15 - Friday, 16th June, Aula Maxima, Ground Floor)