Deletion of the Hippo core kinases MST1 and MST2 by siRNA rescues liver regeneration in aged mice


The Hippo pathway controls organ size through cell proliferation and apoptosis through regulation of the co-transcription factor Yap1. The liver regenerates following the loss or damage of hepatic tissue, however in some... [ view full abstract ]


  1. Giulio Loforese (University of Bern)
  2. Thomas Malinka (Inselspital, Universtiy of Bern)
  3. Adrian Keogh (University of Bern)
  4. Thanos Halazonetis (University of Geneva)
  5. Daniel Candinas (Inselspital, Univeristy Hosptial Bern)
  6. Deborah Stroka (Inselspital, University of Bern)

Topic Area

Liver regeneration


OS8 » Session 8 Liver Regeneration (09:30 - Saturday, 17th June, Aula Maxima, Ground Floor)