Stability and drug release of anti-cardiac hypertrophic peptide loaded in new nanohybrids based on gold nanoparticles embedded into a polymeric matrix

Sabrina Sepulveda Rivas

Universidad de Chile

My name is Sabrina Sepúlveda Rivas, Medical Technology and PhD (C) in Pharmacology with focus in cardiovascular nanomedicine at the University of Chile.  During my PhD I develop an effective drug delivery system that can transport and controlled drug release. Also I evaluate the influence of our recently developed Eudragit E-alginate (EE-Alg) nanoparticles on cell viability and cell morphology. Then, I investigate the colloidal stability and the release profiles of a peptide with excellent properties for cardiovascular therapy. In order to increase our understanding of its potential biomedical applications.


Introduction Angiotensin-(1-9) has been reported as a peptide of renin-angiotensin system (RAS) and a novel anti-cardiac hypertrophy agent (1). The clinical application of Angiotensin-(1-9) is restricted due to its... [ view full abstract ]


  1. Sabrina Sepulveda Rivas (Universidad de Chile)
  2. Javier Morales (Universidad de Chile)
  3. Maria Paz Ocaranza (Pontificia Universidad Católica de Chile)

Topic Area

Targeted drug delivery and nanocarriers


PS3 » Poster Session (13:30 - Wednesday, 27th September, Gallery)

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