Apoferritin-affibody conjugates for cancer therapy

Neil Thomas

University of Nottingham

1987 BSc(Hons) Chemistry 1st Class, University of Southampton, UK1990 PhD Mechanistic Enzymology, Southampton (Prof. D. Gani), UK1990-92 NATO/SERC Fellow Pennsylvania State University (Prof. S.J. Benkovic), USA1992-1995 Royal Society University Research Fellow and Lecturer, School of Chemistry, University of Bath, UK1995-2003 Royal Society University Research Fellow and Lecturer, School of Chemistry, University of Nottingham, UK2003-2008 Senior Lecturer/Associate Professor, School of Chemistry, University of Nottingham, UK2008-present Professor of Medicinal & Biological Chemistry, School of Chemistry, Centre for Biomolecular Sciences, University of Nottingham, UK

Abstract

Introduction Apoferritin is a ubiquitous protein nanocage, 12 nm in diameter with an 8 nm diameter hollow core that is used in nature as a store for up to 4,500 iron (III) ions forming ferritin. Removal of the Iron(III)... [ view full abstract ]

Authors

  1. Neil Thomas (University of Nottingham)
  2. Lei Zhang (University of Nottingham)
  3. Tracey Bradshaw (University of Nottingham)

Topic Areas

Targeted drug delivery and nanocarriers , Nanomedicine for cancer diagnosis & therapy , Nano-Imaging for diagnosis, therapy and delivery

Session

OS2b-207 » Nano-Imaging for diagnosis, therapy and delivery (16:30 - Tuesday, 26th September, Room 207)

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