A Synthetic Macromolecule to Reverse Heparin Anticoagulation and Profibrinolytic Activity without Altering Clot Morphology

Abstract

Heparin anticoagulants are mainstay in the treatment of thrombosis. However, anticoagulation associated haemorrhage is a major concern; an antidote is required to restore hemostasis. Protamine sulphate (PS), a cationic... [ view full abstract ]

Authors

  1. Manu Thomas Kalathottukaren (University of British Columbia)
  2. Libin Abraham (University of British Columbia)
  3. Rajesh Shenoi (University of British Columbia)
  4. Federico Rosell (University of British Columbia)
  5. Charles Haynes (University of British Columbia)
  6. Jayachandran Kizhakkedathu (University of British Columbia)

Topic Areas

Topics: Platform Technologies & Biomaterials , Topics: Other

Session

BM1 » Platform Technologies & Biomaterials (08:30 - Saturday, 10th September, Max Bell Auditorium)