Direct differentiation of hepatic stellate cells from ips cells

Abstract

Background: The development of complex hepatic in vitro systems and artificial liver devices has been hampered by the lack of reliable source of human liver cells. Here we report an efficient protocol to direct the... [ view full abstract ]

Authors

  1. Julia Vallverdu (Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))
  2. Mar Coll (Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))
  3. Luis Perea (Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))
  4. Ruben Boon (Stem Cell Institute Leuven, Leuven, Belgium)
  5. Sofia B. Leite (Liver Cell Biology Lab, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB))
  6. Ayla Smout (Liver Cell Biology Lab, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB))
  7. Adil El Taghdouini (Liver Cell Biology Lab, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB))
  8. Delia Blaya (Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))
  9. Daniel Rodrigo-Torres (Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))
  10. Isabel Graupera (Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))
  11. Beatriz Aguilar (Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))
  12. Christophe Chesne (Biopredic International,France)
  13. Mustapha NAJIMI (Laboratory of Pediatric Hepatology and Cell Therapy, Université Catholique de Louvain (UCL), Belgium)
  14. Etienne Sokal (Laboratory of Pediatric Hepatology and Cell Therapy, Université Catholique de Louvain (UCL), Belgium)
  15. Juan José Lozano (Centro de Investigación Biomèdica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain)
  16. Leo A. Van Grunsven (Liver Cell Biology Lab, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel (VUB))
  17. Catherine M Verfaillie (Stem Cell Institute Leuven, Leuven, Belgium)
  18. Pau Sancho Bru (Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS))

Topic Area

Liver fibrosis

Session

OS9 » Session 9 Hepatic Stellate Cells (11:30 - Saturday, 17th June, Aula Maxima, Ground Floor)