C5a receptor antagonist treatment in TLR4 mutant C3H/HeJ mouse negatively effects the liver regeneration after partial hepatectomy

Abstract

Keywords: Liver regeneration, Partial hepatectomy, Complement system, C5a, C3H/HeJ mice Following partial hepatectomy (PH), gut derived LPS acts as a signal for LPS/TLR4 and Complement pathways. Complement activation leads to... [ view full abstract ]

Authors

  1. Rahiman Faiyaz (National university of Ireland, Galway, Ireland)
  2. Muhamad Marlini (National university of Ireland, Galway)
  3. Beth Mallard (National university of Ireland, Galway)
  4. Niamh Leonard (National university of Ireland, Galway)
  5. Antony Wheatley (National university of Ireland, Galway)

Topic Area

Liver regeneration

Session

PS » Poster Session & Lunch (12:45 - Friday, 16th June, Aula Maxima, 1st Floor)