Involvement of liver macrophages in the pathogenesis of MCD-diet induced NASH in an immunodeficient mouse model

Sandra Winkler

University of Leipzig - Applied Molecular Hepatology Lab

Dr. Sandra Winkler Career Since 16th December 2014 Post-Doc fellow University of Leipzig Applied Molecular Hepatology Lab Leader: Prof. Dr. Bruno Christ 15th November 2011 – 15th December 2014 PhD student University of Leipzig Applied Molecular Hepatology Lab Leader: Prof. Dr. Bruno Christ PhD Thesis: Investigations of the therapeutic application of mesenchymal stem cells in chronic liver diseases, e.g. Non-alcoholic steatohepatitis 15th November 2010 – 14th November 2010 PhD student Martin-Luther University Halle-Wittenberg Applied Molecular Hepatology Lab Leader: Prof. Dr. Bruno Christ 13th April 2010 – 14th November 2010 Research assistant Martin-Luther University Halle-Wittenberg Molecular Hepatology Lab Leader: Prof. Dr. Bruno Christ 01st March 2009 – 12th April 2010 Diploma student Martin-Luther University Halle-Wittenberg Molecular Hepatology Lab Leader: Prof. Dr. Bruno Christ ___________________________________________________________________ Advanced Training Since 09/2014 Post gradual studies of toxicology and environmental protection University of Leipzig Studies 2004 - 2010 Nutritional Sciences Martin-Luther-University Halle-Wittenberg Diploma, Thesis: Establishment of a NASH animal model for cell transplantation in immunodeficient mice 

Abstract

Background/Aims: The innate and the adaptive immune system seem to be pivotal in the development of inflammation in NASH. The aim was to demonstrate that the innate immune system was sufficient to mediate inflammation in the... [ view full abstract ]

Authors

  1. Sandra Winkler (University of Leipzig - Applied Molecular Hepatology Lab)
  2. Stefan Kalkhof (University of Coburg of applied science and art)
  3. Sandra Brückner (Universtity of Leipzig - Applied Molecular Hepatology Lab)
  4. Madlen Hempel (University of Leipzig - Applied Molecular Hepatology Lab)
  5. Ina Bosse (University of Leipzig - Applied Molecular Hepatology Lab)
  6. Sven Baumann (Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research GmbH – UFZ)
  7. Martin Von Bergen (Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research GmbH – UFZ)
  8. Bruno Christ (Universtity of Leipzig - Applied Molecular Hepatology Lab)

Topic Area

Liver sinusoidal liver cells in liver disease

Session

OS7 » Session 7 Liver Fibrosis - 2 (11:15 - Friday, 16th June, Aula Maxima, Ground Floor)