PIM kinase inhibition decreases tumor initiating cell phenotype in hepatoblastoma


Objective:We previously demonstrated that PIM3 promoted tumorigenesis in a human hepatoblastoma (HB) cell line, HuH6. Tumor initiating cells (TICs) are a subpopulation of cells responsible for tumor resistance and recurrence.... [ view full abstract ]


  1. Laura Stafman (University Of Alabama At Birmingham, Department Of Surgery)
  2. Smitha Mruthyunjayappa (UAB)
  3. Evan Garner (UAB)
  4. Jamie Aye (UAB)
  5. Jerry Stewart (UAB)
  6. Karina Yoon (UAB)
  7. Stuart Cramer (University of South Carolina)
  8. elizabeth beierle (Children's of Alabama)

Topic Areas

Pediatric Surgery , Surgical Oncology


Plenary » Plenary Scientific Session (10:25 - Friday, 22nd September, Bradley Lecture Center)