Wilms tumor patient-derived xenografts recapitulate the histology and genetic features of high-risk human primary Wilms tumor
Abstract
Objective: To establish a Wilms tumor patient-derived xenograft (WTPDX) library that recapitulates the genetic and histologic features of primary Wilms tumor (WT). Methods: Forty-five heterotopic WTPDX were established in... [ view full abstract ]
Authors
- Andrew Murphy (St. Jude Children's Research Hospital)
- Emilia Pinto (St. Jude Children's Research Hospital)
- Michael Clay (St. Jude Children's Research Hospital)
- Christopher Morton (St. Jude Children's Research Hospital)
- Rani George (Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School)
- Andrew Davidoff (St. Jude Children's Research Hospital)
- Gerard Zambetti (St. Jude Children's Research Hospital)
Topic Area
Pediatric Surgery
Session
QS-Peds » Quick-Shot Presentations: Pediatric Surgery (15:00 - Thursday, 21st September, Dearth Tower Conf 1)