Using Gene Set Enrichment Analysis to Create Polygenic Risk Scores for Childhood Externalizing Behavior

Abstract

GWAS-based polygenic risk scores (PRS) for childhood externalizing behavior have predicted aggression, impulsiveness, and conscientiousness (Salvatore et al., 2015). Selection of SNPs for PRS is typically statistically-driven,... [ view full abstract ]

Authors

  1. Kit Elam (Arizona State University)
  2. Charles Beekman (Arizona State University)
  3. Thomas Dishion (Arizona State University)
  4. Daniel Shaw (University of Pittsburgh)
  5. Melvin Wilson (University of Virginia)
  6. Kathryn Lemery-chalfant (Arizona State University)

Topic Areas

Statistical Methods , Psychopathology (e.g., Internalizing, Externalizing, Psychosis)

Session

3B-OS » Developmental Disorders (15:30 - Thursday, 29th June, Sal D)

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