This investigation has been carried out with financial support from RSF (16-18-10222)
The study of the influence of diplotypes genes of neurotransmitter systems on personal characteristics - important topic of modern researches.
The aim of the study is to investigate the personality traits of women, carriers of different diplotypes on polymorphic loci Val158Met COMT (GG, GA, AA) and –uVNTR MAOA (H, L, M). Participants: 115 women 18-24 years old.
Methods. Genotyping; psychodiagnostics: Buss-Durkee Hostility Inventory, Thomas K.W. test, Questionnaire of formal-dynamic properties of individuality, Diagnostication of personal inclination to deviant behavior.
Statistical processing: ANOVA, discriminant analysis, p≤0,01.
Results.
Women with heterozygous diplotype (MAOA M + GA COMT) display low level of aggression and medium intellectual rate;
Carriers of diplotype MAOA L + GA COMT are characterized as having high degree of aggression, negativism and communicative plasticity; they also usually display competitive strategies in conflict situations;
Women with diplotype MAOA H + GA COMT show low level of aggression, high degree of intellectual ergicity; they can be characterized as conformal;
Women with high-activity diplotype (MAOA H + GG COMT) have sanguine temperament; they display high level of aggression, intellectual rate and activity; they show low degree of emotionality in communication, tend to be conformal and do not usually take offence.
Carriers of diplotype MAOA M + AA COMT have melancholic temperament, display low level of aggression, slow intellectual rate and decreased activity; they show high emotionality in communication as well as low communicative plasticity; they tend to take offence and behave in non-conformal ways.
As seen from stated above, the psychological portraits we describe include antagonistic psychological characteristics. That is why we can suggest that some combinations of genotypes MAOA and COMT might have the mutually opposite impact and that could probably be so due to the peculiarities of neurotransmitter metabolism.
