Results from the largest GWAS of lifetime cannabis use (N=184,765): new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use

Abstract

Cannabis use is a heritable trait that has been associated with adverse mental health outcomes. To identify genetic risk variants, we performed the largest genome-wide association study for lifetime cannabis use (N=184,765) to... [ view full abstract ]

Authors

  1. Karin Verweij (Department of Psychiatry, Academic Medical Centre)
  2. Joëlle Pasman (Radboud University)
  3. International Cannabis Consortium (University of Amsterdam)
  4. 23andme Research Team (NA)
  5. Nathan Gillespie (Virginia Institute for Psychiatric and Behavior Genetics)
  6. Eske Derks (QIMR-Berghofer Medical Research Institute)
  7. Jacqueline Vink (Radboud University)

Topic Area

Substance use: Alcohol, Nicotine, Drugs

Session

OS-7B » Substance Use (16:40 - Friday, 22nd June, Yellowstone)

Paper

BG2018.pdf

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