Investigating the causal relationships between mental and physical health outcomes using Mendelian randomization

Abstract

Mendelian Randomization (MR) is a statistical genetics approach that allows inferring causal relationships between human traits and health outcomes using genetic variants as instrumental variables. Specifically, 2-sample MR... [ view full abstract ]

Authors

  1. Chia-Yen Chen (Analytic and Translational Genetics Unit & Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard)
  2. Jordan Smoller (Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard)
  3. Benjamin Neale (Analytic and Translational Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard)

Topic Areas

Cognition: Education, Intelligence, Memory, Attention , Developmental Disorders (e.g. ADHD) , Health (e.g., BMI, Exercise) , Psychopathology (e.g., Internalizing, Externalizing, Psychosis) , Statistical Methods

Session

OS-8A » Statistical Methods II (10:30 - Saturday, 23rd June, Auditorium)

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