A human iPS cell-based model of medulloblastoma demonstrates co-operativity between SHH signalling and mutation in an epigenetic modifier


Objective: Medulloblastoma (MB), the most common malignant pediatric brain tumor, is comprised of four subgroups (WNT, SHH, Group 3, Group 4).  While recurrent single nucleotide variations is rare in MB, mutation of... [ view full abstract ]


  1. Jignesh Tailor (St George's University Hospital, London)
  2. Miller Huang (University of California San Francisco)
  3. Austin Smith (University of Cambridge)
  4. William Weiss (University of California San Francisco)

Topic Areas

Laboratory and Clinical Science , Paediatric Oncology and Tumours in Young Adults


OS-22D » Parallel Session D: Science (16:00 - Thursday, 22nd June, Pentland East)

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