Replication stress drives constitutive activation of the DNA damage response and consequent radioresistance in glioblastoma cancer stem cells


INTRODUCTION Glioblastoma (GBM)is a lethal primary brain tumour characterised by treatment resistance and inevitable recurrence, both of which are driven by a subpopulation of glioblastoma cancerstem cells (GSCs) with... [ view full abstract ]


  1. Ross Carruthers (University of Glasgow)
  2. Shafiq Ahmed (University of Sunderland)
  3. Shaliny Ramachandran (University of Oxford)
  4. Ester Hammond (University of Oxford)
  5. Anthony Chalmers (Beatson West of Scotland Cancer Centre)

Topic Area

Laboratory and Clinical Science


OS-22D » Parallel Session D: Science (16:00 - Thursday, 22nd June, Pentland East)

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