Research update by the European Network for the Investigation of Gender Incongruence (ENIGI)

Background

The number of trans persons seeking gender affirming treatment is still increasing. Due to the relatively low prevalence of the condition and small number of specialized centers, international collaboration is warranted. The... [ view full abstract ]

Aim(s)

During this symposium, the researchers of ENIGI, will describe the study design and protocol, study objectives, and current results of the study. Furthermore, they will share their experience with endocrine care of... [ view full abstract ]

Main Outcome Measures

The ENIGI is a multicenter prospective study. For the endocrine part of the ENIGI study, four European treatment centers, in Ghent, Oslo, Florence, and Amsterdam, developed a standardized study and treatment protocol. [ view full abstract ]

Methods

Outcome measures include hormonal and metabolic parameters, bone density, secondary sex and anthropometric characteristics, and physical and psychological well-being during cross-sex hormonal treatment (CHT). [ view full abstract ]

Results

From February 2010 until May 2016, 1092 transgender persons were included in the study of which 576 persons were trans men and 516 persons were trans women. These numbers still rise since the inclusion is still ongoing. During... [ view full abstract ]

Conclusion

The ENIGI initiative is one of the biggest collaborations performing research on safety and effectiveness of current hormonal treatment protocols. In order to provide the audience more insight in the ins and outs of the... [ view full abstract ]

Authors

Christel de Blok (VU University Medical Center, Department of Endocrinology and Center of Expertise on Gender Dysphoria, Amsterdam), Nienke Nota (VU University Medical Center, Department of Endocrinology and Center of Expertise on Gender Dysphoria, Amsterdam), Justine Defreyne (Ghent University Hospital, Department of Endocrinology and Center for Sexology and Gender, Ghent), Maartje Klaver (VU University Medical Center, Department of Endocrinology and Center of Expertise on Gender Dysphoria, Amsterdam), Chantal Wiepjes (VU University Medical Center, Department of Endocrinology and Center of Expertise on Gender Dysphoria, Amsterdam), Alessandra Daphne Fisher (Careggi University Hospital, Sexual Medicine and Andrology Unit, Department of Experimental, Clinical and Biomedical Sciences, Florence), Thomas Schreiner (Oslo university hospital, Department of Endocrinology, Oslo), Martin den Heijer (VU University Medical Center, Department of Endocrinology and Center of Expertise on Gender Dysphoria, Amsterdam), Guy T'Sjoen (Ghent University Hospital, Department of Endocrinology and Center for Sexology and Gender, Ghent)

Topic Area

Topics: Endocrinology treatment (basic level): pre and post op hormone treatment

Session

MW-2E » Research Update by the European Network for the Investigation of Gender Incongruence (ENIGI) (16:00 - Friday, 7th April, Atlantic 2)

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