Can oestrogen suppress androgen production in male to female transsexuals

Antiandrogen use in male to female transgender patients is recommended by a variety of guidelines. Some clinics had, prior to these guidelines, not routinely used antiandrogen therapy - and there are some reports of up to 60%... [ view full abstract ]

Antiandrogen use in male to female transgender patients is recommended by a variety of guidelines. Some clinics had, prior to these guidelines, not routinely used antiandrogen therapy - and there are some reports of up to 60% not requiring the addition of antiandrogen therapy as oestrogen use itself can suppress androgen production in certain individuals.

To establish the proportion of male to female transgender patients presenting to the Sandyford Gender Service who suppress androgen production with oestrogen alone. [ view full abstract ]

To establish the proportion of male to female transgender patients presenting to the Sandyford Gender Service who suppress androgen production with oestrogen alone.

A retrospective sample of male to female transgender people referred to the Gender Service in 2011/2012 was used. Their clinical notes were analysed using an Excel database. [ view full abstract ]

A retrospective sample of male to female transgender people referred to the Gender Service in 2011/2012 was used. Their clinical notes were analysed using an Excel database.

Proportion patients referred in 2011/2012 to the Sandyford Gender Service who suppress testosterone on oestrogen alone. [ view full abstract ]

Proportion patients referred in 2011/2012 to the Sandyford Gender Service who suppress testosterone on oestrogen alone.

19.3% of the sample did suppress testosterone on oestrogen alone. This number may have been higher in reality as a proportion of patients were placed on antiandrogens without being given the opportunity to self-suppress on... [ view full abstract ]

19.3% of the sample did suppress testosterone on oestrogen alone. This number may have been higher in reality as a proportion of patients were placed on antiandrogens without being given the opportunity to self-suppress on oestrogen alone.

There is a group of patients who will suppress androgen production without the need for antiandrogen use. This may reduce exposure to additional side effects and associated risk. We recommend that male to female transgender... [ view full abstract ]

There is a group of patients who will suppress androgen production without the need for antiandrogen use. This may reduce exposure to additional side effects and associated risk. We recommend that male to female transgender patients should be offered a choice around the prescription of antiandrogen therapy after being fully informed of the potential of self-suppression.