Cross-sex hormone treatment and psychobiological changes in transsexual persons: Two-year follow-up data

Background

To date, there are few studies investigating the impact of body changes induced by cross-sex hormonal treatment (CHT) on psychobiological well-being in gender-dysphoric persons (GDs). [ view full abstract ]

Aim(s)

The objective of the study was to assess whether CHT-related body changes affect psychobiological well-being in GDs. [ view full abstract ]

Methods

A consecutive series of 359 GDs was considered for a cross-sectional section of the study. In addition, 54 GDs were studied in a 2-year follow-up. [ view full abstract ]

Main Outcome Measures

A physical examination was performed, including body mass index, waist circumference, and hair distribution. We also evaluated breast development and testis volume in male to female subjects and clitoris length in female to... [ view full abstract ]

Results

The following results were found: 1) GDs undergoing CHT reported significantly lower subjective levels of GD, body uneasiness, and depressive symptoms as compared with those without; 2) CHT-induced body modifications were... [ view full abstract ]

Conclusion

The aforementioned results support the efficacy of CHT intervention in improving subjective perception of one’s own body, which was partially associated with objective changes. [ view full abstract ]

Authors

  1. Alessandra Fisher (Department of Experimental, Clinical and Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Florence)
  2. Giovanni Castellini (Department of Experimental, Clinical and Biomedical Sciences Careggi University Hospital; Psychiatric Unit, University of Florence)
  3. Jiska Ristori (Department of Experimental, Clinical and Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Florence)
  4. Helen Casale (Department of Experimental, Clinical and Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Florence)
  5. Emanuele Cassioli (Department of Experimental, Clinical and Biomedical Sciences Careggi University Hospital; Psychiatric Unit, University of Florence)
  6. Carolina Sensi (Department of Experimental, Clinical and Biomedical Sciences Careggi University Hospital; Psychiatric Unit, University of Florence)
  7. Egidia Fanni (Department of Experimental, Clinical and Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Florence)
  8. Anna Maria Letizia Amato (Department of Experimental, Clinical and Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Florence)
  9. Eva Bettini (Department of Experimental, Clinical and Biomedical Sciences, Sexual Medicine and Andrology Unit, University of Florence, Florence)
  10. Maddalena Mosconi (Hospital S.Camillo-Forlanini, Gender Identity Development Service)
  11. Davide Dèttore (Department of Health Sciences, University of Florence)
  12. Valdo Ricca (Psychiatric Unit, University of Florence)
  13. Mario Maggi (Department of Experimental, Clinical and Biomedical Sciences Careggi University Hospital)

Topic Area

Oral & Poster Topics: Endocrinology

Session

OS-1C » Endocrinology I (14:00 - Thursday, 6th April, Atlantic 3)

Presentation Files

The presenter has not uploaded any presentation files.