Complete 3D regeneration of functional organs by manipulation of the pluripotent stem cells

Complete regeneration of the functional organs have been very difficult in many biological species. We have been challenged the regeneration of the functional organs by use of the pluripotent stem cells isolated from early... [ view full abstract ]

Complete regeneration of the functional organs have been very difficult in many biological species. We have been challenged the regeneration of the functional organs by use of the pluripotent stem cells isolated from early avian embryos. These stem cells were cultured, genetically modified and micro-injected into the other avian embryos. Completely functional legs and hearts could be regenerated and the organ shape in 3D level were almost same as that of the control organs. Moreover, the mice ES cells could be committed into avian embryos and the mice derived neuron or muscle could be regenerated in the avian embryos.
All of the experimental procedures and results of the regeneration of the stem cell-derived organs will be shown as movie.