Salinomycin nanoparticles induce selective toxicity toward tumor cells rather than stroma in orthotopic model of pancreatic cancer

zahra Daman

Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

I was born in Tehran (Iran) and graduated with a PharmD degree from the first ranked Iranian medical university, Tehran University of Medical Sciences, in 2010. I continued my study towards obtaining a PhD on pharmaceutics in order to enhance my knowledge on designing novel pharmaceutical delivery systems. My current research focus is on developing DDS using nanoparticles for cancer chemotherapy. In Fall 2014 to Spring 2015, I enjoyed a sabbatical leave in the labs of prof. Leaf Huang at University of North Carolina in Chapel Hill (NC, USA), which was a great experience to broaden my skills and developments.

Abstract

Introduction Salinomycin (SAL), a selective inhibitor of cancer stem cells (CSCs), was recently recognized for its ability to inhibit proliferation and induce apoptosis in various tumors including highly chemo-resistant ones.... [ view full abstract ]

Authors

  1. zahra Daman (Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran)
  2. Yuhua Wang (Laboratory of drug targeting, Eshelman School of Pharmacy, University of North Carolina in Chapel Hill, NC, USA)
  3. Leaf Huang (Laboratory of drug targeting, Eshelman School of Pharmacy, University of North Carolina in Chapel Hill, NC, USA)

Topic Area

Nanomedecine for cancer diagnosis & therapy

Session

PS2 » Poster Session & Sponsors Exhibition (13:30 - Thursday, 29th September, Patio 25)

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