Nanotechnology based materials to repair and rebuild human organs

Nanotechnology is revolutionising the repair and replacement of human organs. Nanomaterials have the unique physical, chemical, mechanical, and optical properties that naturally occur at that nano scale. We have developed a... [ view full abstract ]

Nanotechnology is revolutionising the repair and replacement of human organs. Nanomaterials have the unique physical, chemical, mechanical, and optical properties that naturally occur at that nano scale. We have developed a family of nanocomposite materials for clinical application. The nanocomposite materials have been used in repair and development of human organs. The materials have been fabricated to the 3D scaffold using coagulation, casting, electrospinning as well as 3D printing. Then the scaffold has been functionalised with bioactive molecules and antibodies for capturing and differentiation of stem cells to mature cells either in vitro or in vivo using the body as a bioreactor. In this talk present to development as well as route of taking laboratory research to patients and commercialisation. The organs will be discussed in details world first synthetic trachea, tear ducts, small diameter bypass graft for replacement of coronary and vascular arteries. Taking organs to patients and commercialisation is challenging in term of regulatory as well as manufacturing under GMP/GLP. In this talk will discuss the pathway and time scale taking the organs to the clinical trial from laboratories products. Finally, will discuss our experience in development of nanoparticles and its application in diagnostic and treatment of cancer. These nanoparticles include quantum dots, magnetic nanoparticles and carbon nanotube.