Improving 131I radioiodine therapy by hybrid metal-polymer nanoparticles
Béatrice Cambien
TIRO, UMRE 4320, BIAM, DRT, CEA, Université de Nice-Sophia Antipolis
Beatrice Cambien is a researcher at INSERM, the French organization of medical research. For more than 12 years now, she has been working in the field of cancer, her projects being dedicated to unravel key factors involved in tumour progression and to target those factors for therapy. More recently, her work drifted towards the field of radiation oncology. Her current research mainly focuses on sensitizing tumours to distinct types of radiation (X-rays, protons but also radioiodine-induced ionizations) by using distinct types of metallic nanoparticles. Today, she is presenting her work aiming at: Improving 131I radioiodine therapy by hybrid metal-polymer nanoparticles.
Abstract
Introduction 131I radioiodine therapy is very performant in the treatment of thyroid cancer metastases. Applicability of this approach combined with gene therapy (transfer of the Na/I symporter gene into tumors)... [ view full abstract ]
Authors
- Béatrice Cambien (TIRO, UMRE 4320, BIAM, DRT, CEA, Université de Nice-Sophia Antipolis)
- Marie Paquet (TIRO, UMRE 4320, BIAM, DRT, CEA, Université de Nice-Sophia Antipolis, France)
- Marine Le Goas (NIMBE UMR 3685, CEA, CNRS, Université Paris-Saclay, CEA Saclay 91191 Gif sur Yvette Cedex)
- Aurélie Paquirissamy (NIMBE UMR 3685, CEA, CNRS, Université Paris-Saclay, CEA Saclay 91191 Gif sur Yvette Cedex)
- Geraldine Carrot (NIMBE UMR 3685, CEA, CNRS, Université Paris-Saclay, CEA Saclay 91191 Gif sur Yvette Cedex)
- Jean-Philippe Renault (NIMBE UMR 3685, CEA, CNRS, Université Paris-Saclay)
- Thierry Pourcher (TIRO, UMRE 4320, BIAM, DRT, CEA, Université de Nice-Sophia Antipolis)
Topic Area
Nanomedicine for cancer diagnosis & therapy
Session
OS3b-A » Nanomedicine for cancer diagnosis & therapy (16:50 - Wednesday, 27th September, Auditorium)
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