Distribution of genetic polymorphisms of genes implicated in thiopurine drugs metabolism

Abstract

Introduction:Thiopurine-S-methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) are crucial enzymes involved in the metabolism of thiopurine drugs: azathioprine and 6-mercaptopurine, used in the treatment of... [ view full abstract ]

Authors

  1. Zohra CHADLI (Pharmacology Department, University Hospital, Monastir, Tunisia. Faculty of Medicine, University of Monastir, Tunisia.)
  2. Emna Kerkeni (Pharmacology Department, University Hospital, Monastir, Tunisia. Faculty of Medicine, University of Monastir, Tunisia.)
  3. Ibtissem Hannachi (Pharmacology Department, University Hospital, Monastir, Tunisia. Faculty of Medicine, University of Monastir, Tunisia.)
  4. Saoussen Chouchene (Hematology Laboratory and Blood Bank, University Hospital, Monastir, Tunisia)
  5. Nadia Ben Fredj (Pharmacology Department, University Hospital, Monastir, Tunisia. Faculty of Medicine, University of Monastir, Tunisia.)
  6. Amel Chaabane (Pharmacology Department, University Hospital, Monastir, Tunisia. Faculty of Medicine, University of Monastir, Tunisia.)
  7. Naceur Boughattas (Pharmacology Department, Faculty of Medicine, University of Monastir, Tunisia.)
  8. Karim Aouam (Pharmacology Department, University Hospital, Monastir, Tunisia. Faculty of Medicine, University of Monastir, Tunisia.)

Topic Area

Personalized therapies (cancer, immunology, infectious diseases, clinical case studies, et

Session

PS3 » Poster Session (13:30 - Wednesday, 27th June, Main hall)

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