Global DNA (hydroxy)methylation is not associated to MTX response at 3 months in early RA patients


Introduction: Methotrexate (MTX) is first-line therapy in early rheumatoid arthritis (eRA). ~20-40% of patients does not benefit from therapy and switch medication. Immediate effective therapy is crucial to restrain joint... [ view full abstract ]


  1. Helen Gosselt (Erasmus University Medical Hospital)
  2. Bertrand Van Zelst (Erasmus University Medical Hospital)
  3. Mieke Hazes (Erasmus University Medical Hospital)
  4. Robert De Jonge (VU University Medical Hospital)
  5. Sandra Heil (Erasmus University Medical Hospital)

Topic Areas

Integrating Big Data (genome data, pharmacogenomics, therapeutic applications of genome ed , Drug target discovery and integration with individualized therapy, integration of diagnosi , Personalized therapies (cancer, immunology, infectious diseases, clinical case studies, et


PS3 » Poster Session (13:30 - Wednesday, 27th June, Main hall)

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