Phase Genomics utilizes genomic proximity information from in vivo Hi-C to scaffold end-to-end reference-quality genomes and produce unparalleled metagenome assemblies.
Approaching genome scaffolding in a fundamentally new way, our Proximo™ Hi-C platform measures the proximity of DNA in vivo and uses this information to scaffold end-to-end chromosomes for plant and animal genomes. It only requires a small amount of biological sample in its natural, intact state — no need to isolate high-molecular weight DNA. The ultra-high contiguity of resultant chromosome-scale scaffolds replaces the need for genetic mapping and manual scaffolding efforts.
Our ProxiMeta™ metagenomic deconvolution platform uses Hi-C interaction data to detect which DNA sequences originated in the same cell, enabling assembly of whole genomes from mixed samples in their natural state — no culturing or high-molecular-weight DNA extraction required. This powerful new source of information allows sequences from the same species and/or strain to be grouped, yielding dozens or even hundreds of reference-quality genomes for rare, unculturable, and novel microbes easily and affordably.
Dedicated to delivering scientific excellence and attentive service, we genuinely care about your successful outcomes. We are collaborative, flexible and uniquely qualified to deliver the most complete and accurate results.
For more information, email us at info@phasegenomics.com
Sequencing strategies and technology advancements using the various NGS platforms , Single cell and metagenomic assemblies
