Still Using Tips for NGS Sample Prep? Acoustic Droplet Ejection

Sound waves move fluids with unprecedented precision in billionth-of-a-liter increments and completely bypass the myriad issues with pipettes. Without tips, nozzles, or valves, acoustic droplet ejection (ADE)-based liquid... [ view full abstract ]

Sound waves move fluids with unprecedented precision in billionth-of-a-liter increments and completely bypass the myriad issues with pipettes.

Without tips, nozzles, or valves, acoustic droplet ejection (ADE)-based liquid handlers allow for touchless transfer between machine and samples, providing real control over liquids with precision and accuracy while drastically reducing environmental waste and associated costs.

In an era of tight budgets and lean resources, Labcyte customers are realizing drastically increased numbers of libraries generated with low-volume, multiplexed next-generation sequencing (NGS) library preparation methods using the Echo® 525 Liquid Handler by reducing transfer volumes by 75% or more.

In addition to cost savings, we demonstrate an increase in sample-processing throughput with the Echo system due to efficient multiplexing, barcoding, and a combinatorial pooling strategies that can be applied to workflows beyond NGS.